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Advisor:
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Department of
Statistics
Research
Interests •
Identifying genes for complex disorders with multiple quantitative traits •
Association and Linkage studies • Large
and complex pedigrees • Copy
Number Variation •
High-density SNPs data •
Multivariate phenotypes •
Bayesian MCMC methods for mapping genes in complex pedigrees •
Likelihood ratio test under the non-standard boundary condition Methodological
research • Asymptotic distributions of likelihood ratio tests in variance
components model under nonstandard
boundary condition • Assessing the power of multivariate tests for identifying QTLs for complex traits Collaborative
Research At Dr. Elena Grigorenko Lab in • population isolated in •
Genome-Wide linkage and association for developmental dyslexia (2006-present) •
Autism candidate gene association analysis with genes controlling affiliative behavior (OXT, OXTR, PRL, PRLR, D¥âH, and FOSB)
(2006-2007) •
Autism candidate gene association analysis with MIF gene (Macrophage
Migration Inhibitory Factor) (2006-2007) Publications Carolyn M. Yrigollen,
Summer
S. Han, Anna Kochetkova, Tammy Babitz, Joseph T. Chang, Fred R. Volkmar,
James F. Leckman, and Elena L. Grigorenko Genes Controlling Affiliative Behavior as
Candidate Genes for Autism Volume
63, Issue 10, Pages 911-916, 2008 Biological Psychiatry Elena
L. Grigorenko, Summer S. Han, Carolyn M. Yrigollen,
Lin Leng, Courtney McDonald, Yuka Mizue, George M. Anderson, Erik J. Mulder,
Annelies de Bildt, Ruud B. Minderaa, Fred R. Volkmar, Joseph T. Chang, Richard Bucala Macrophage Migration Inhibitory
Factor and Autism Spectrum Disorders Volume
122, No.2, Pages e438–e445, 2008 Pediatrics Summer S. Han and Joseph T. Chang Reconsidering the asymptotic
null distributions of a likelihood ratio test for multivariate genetic
linkage in variance components model (Under review) (manuscript) Summer S. Han, Elena L. Grigorenko and Joseph T. Chang A more robust and efficient
multivariate method for identifying QTLs for
complex traits (Manuscript in preparation) Conference presentations 2008 JSM (Joint Statistical Meetings), Title: A note on asymptotic null
distribution of likelihood-ratio test of multivariate genetic linkage in
variance components model 2008 IGES (International Genetic Epidemiology Society), Title: A note on asymptotic null
distribution of likelihood-ratio test of multivariate genetic linkage in
variance components model 2008 ASHG (American Society of Human Genetics), Title:
The power of a multivariate trait-specific test for linkage in complex
disorders with multiple quantitative traits Awards and Fellowships 2008
Joint Statistical Meetings (JSM), Statistics in Epidemiology Section Travel Award Paper Competition (pic) Title:
A note on the asymptotic null distribution of likelihood-ratio tests for
multivariate genetic linkage in variance components models Yale
Graduate Student Assembly Conference
Travel Fund awards (2008) |
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