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Graduate School

Statistics

Biostatistics

Advisor:

Department of Statistics                    

Summer Seongmin Han 4th year Ph.D student Department of Statistics Yale University 24 Hillhouse Avenue New Haven CT 06520 seongmin.han@yale.edu

Research Interests

- Likelihood ratio test under non-standard boundary condition

- Bayesian approach in quantitative loci linkage analysis

- High-density SNPs data

- Gene-mapping in Complex disorder

- Large and complex pedigree

- Multivariate methods in linkage analysis for mapping multiple traits

- Multiple testing adjustment methods

Working papers

- Asymptotic distributions of likelihood ratio test in variance components model under non-standard boundary condition

- Power of multivariate linkage test in variance components using non-centrality parameter of chi-squared distributions

Collaboration projects with EGLab

- OSH project (Mapping genes for Language disorders in complex inbred pedigrees in population isolate in Russia; High-density SNPs markers)

- Whole-genome linkage screen of Developmental Dyslexia

- Autism candidate gene association studies

Publications

Carolyn M. Yrigollen, Summer S. Han, Anna Kochetkova, Tammy Babitz, Joseph T. Chang, Fred R. Volkmar, James F. Leckman, and Elena L. Grigorenko

Genes Controlling Affiliative Behavior as Candidate Genes for Autism (2008)

Biological Psychiatry (Accepted)

Elena L. Grigorenko, Summer S. Han, Carolyn M. Yrigollen, Lin Leng, Courtney McDonald, Yuka Mizue, George M. Anderson, Erik J. Mulder, Annelies de Bildt, Ruud B. Minderaa, Fred R. Volkmar, Joseph T. Chang, Richard Bucala

Macrophage Migration Inhibitory Factor and Autism Spectrum Disorders (2008) Pediatrics (Accepted)

Conference presentation

2008 JSM (Joint Statistical Meetings) conference (scheduled on August 2008)

A note on asymptotic null distribution of likelihood-ratio test of multivariate genetic linkage in variance components model