I think Downey was perhaps inspired by French new-wave.
Who wasn't?
Unfortunately, what he ended up creating here was more along the lines of crackhead new-wave.
A synapse is obviously a terrible thing to lose and Downey appears to have lost plenty.
Just say no, indeed. In more ways than one. Including to watching this film.
I couldn't bear it after a while and began fast forwarding through it. It would have been wiser to have just skipped it altogether.