OK, well, no one in their right mind(s) would pick up a movie titled "The Man with the Screaming Brain" and expect it to be serious. This is an outrageous b-movie, and that means a truly hokey plot, strange characters, clichés, over-the-top action, and oh-so-cheesy one liners. For that odd segment of the population (including myself) that gets a kick out of that kind of thing, this is a gem.
The acting is better than expected. Stacy Keach is embedded in his character. Bruce Campbell brings a spirited, convincing performance. His physical comedy skills are truly impressive in this movie and hearken back to the "Evil Dead" films.